Description
Chemical Properties
| Amino Acid Sequence | Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg |
| Molecular Formula | C101H152N28O22S2 |
| Molecular Weight | 2174.64 g/mol |
| CAS Number | 1627580-64-6 |
| Amino Acids | 16 amino acids |
Description
MOTS-c is a mitochondrial-derived peptide encoded within the 12S rRNA gene of mitochondrial DNA. It is studied for its role in regulating metabolic homeostasis, particularly its effects on glucose metabolism, insulin sensitivity, and energy expenditure. Research has shown MOTS-c to activate AMPK signaling pathways, making it a compound of significant interest in metabolic disease, exercise physiology, and aging research.
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