Description
Chemical Properties
| Molecular Formula | C9H14N4O8P (as ribotide) / C9H14N4O5 (riboside) |
| Molecular Weight | 338.21 g/mol (riboside) |
| CAS Number | 2627-69-2 |
| PubChem CID | 17513 |
Description
AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is a cell-permeable nucleoside analog that acts as a direct activator of AMP-activated protein kinase (AMPK). It is extensively studied as an exercise mimetic due to its ability to stimulate metabolic pathways associated with physical activity, including glucose uptake, fatty acid oxidation, and mitochondrial biogenesis. AICAR remains a foundational research tool in metabolic and exercise physiology studies.
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