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Metabolic Regulators

Tirzepatide

5.0 Reviews

A synthetic 39-amino acid acylated peptide engineered for research into dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor co-agonism, glycemic control, and intensive fat mass reduction.

$130.00

99%+ Purity Tests

Ships from USA

USA Lab Tested

How Tirzepatide Works

Tirzepatide is a first-in-class multi-receptor agonist designed to replicate and enhance the metabolic effects of endogenous incretin hormones. By combining GIP and GLP-1 receptor targeting into a single, structurally optimized molecule, it delivers synergistic metabolic outcomes that surpass single-receptor interventions:

  • Dual-Incretin Receptor Co-Agonism: It targets both the GIP and GLP-1 receptors. While GLP-1 pathways suppress appetite and slow digestion, the integration of GIP receptor activity helps stabilize energy balance, reduces nausea profiles typically seen in pure GLP-1 agents, and optimizes lipid handling directly within adipose tissue.

  • Glucose-Dependent Insulin Secretion: Tirzepatide enhances insulin secretion from pancreatic beta cells in a glucose-dependent manner, meaning it triggers insulin release only when blood glucose levels are elevated. Concurrently, it suppresses inappropriate glucagon secretion, stabilizing overall glycemic fluctuations.

  • Central Appetite Suppression & Delay of Gastric Emptying: It acts directly on neural networks within the hypothalamus and brainstem to decrease appetite, curb reward-driven food cravings, and increase systemic satiety signaling. Peripherally, it delays gastric transit, contributing to prolonged feelings of fullness.

  • Enhanced Insulin Sensitivity and Lipolysis: In metabolic research models, Tirzepatide promotes significant fat mass reduction while protecting lean muscle tissue. It encourages the clearance of ectopic fat stores (such as visceral and hepatic fat) and reverses systemic insulin resistance.

  • Extended Biological Persistence: The peptide backbone contains a $C_{20}$ fatty diacid moiety attached via a hydrophilic linker. This lipid modification enables high-affinity binding to plasma albumin, shielding the molecule from rapid dipeptidyl peptidase-4 (DPP-4) enzymatic breakdown and yielding an extended biological half-life.

Chemical Properties

Property Details
Product Name Tirzepatide Acetate
CAS Number 2023190-10-1
Compound Type Acylated Synthetic Peptide (Dual GIP/GLP-1 Agonist)
Purity Standard 98% or higher purity (verified by HPLC testing)
Appearance Fine white lyophilized powder
pH Range Formulated to sit between ~6.5–7.5 when reconstituted in standard laboratory buffers
Storage (Unopened Powder) Store in the freezer (-20°C). Keep container tightly sealed, dark, and strictly protected from moisture. Stable for 2–3 years.
Storage (Mixed Liquid) Must be stored immediately in the fridge (2°C to 8°C). Highly structural and sensitive to heat; protect from direct UV light, do not freeze the liquid form, and avoid rough shaking.
Intended Use Laboratory Research Only

Additional information

Size

10mg

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Not for human consumption. All products sold by Peptides.US are intended strictly for laboratory and research use only. These products are NOT intended for human or animal consumption. By purchasing from Peptides.US, you confirm that you are at least 21 years of age and that the products will be used solely for legitimate research purposes. These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

Common questions

Find quick answers to the most common questions about our research peptides and product quality.

Research peptides are synthetic compounds commonly used in laboratory and scientific studies to explore biological processes, cellular activity, and protein interactions.

No. All products sold on this website are intended strictly for laboratory and research purposes only and are not approved for human consumption or medical use.

Our peptides are manufactured to meet high research-grade standards and typically test at 99%+ purity through third-party laboratory analysis.

Yes. COAs are available for most products and provide transparency regarding purity, testing, and batch information.
Peptides should be stored in a cool, dry environment away from direct sunlight. After reconstitution, refrigeration is recommended to maintain stability.
Better Peptide focuses on high-purity research compounds, transparent testing standards, fast U.S. shipping, and reliable customer support for research professionals.
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