Description
Chemical Properties
| Molecular Weight | ~3090 g/mol |
| CAS Number | Not yet assigned standard CAS |
| Amino Acids | D-retro-inverso peptide (26 amino acids) |
Description
FOXO4-DRI is a cell-penetrating peptide designed to disrupt the interaction between the FOXO4 transcription factor and p53 in senescent cells. By interfering with this protective mechanism, FOXO4-DRI promotes selective apoptosis of senescent cells while sparing healthy cells. It is a key research compound in the field of senolytics and cellular aging, studied for its potential to reduce the burden of senescent cells and improve tissue function in aging models.
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